Good rule of thumb? Put your luggage in the bathtub when you check in.
To minimize your risk of contact with bed bugs at a hotel, experts say you should first place your luggage in the bathtub – slippery surfaces are difficult for the bugs to cling onto. Continue inspecting your room by examining the bed: check its mattress, piping, and headboard, and pull up the comforters and look for small black dots that resemble ground pepper. See anything suspicious? Speak up, and contact hotel staff immediately.