Tag Archives: LSD

Meet Dr. Albert Hofmann, chemist, and creator of LSD

Meet Dr. Albert Hofmann, chemist, and creator of LSD

Hofmann first synthesized LSD on 16 November 1938. The main intention of the synthesis was to obtain a respiratory and circulatory stimulant (analeptic) with no effects on the uterus in analogy to nikethamide (which is also a diethylamide) by introducing this functional group to lysergic acid. It was set aside for five years, until 16 April 1943, when Hofmann decided to reexamine it. While re-synthesizing LSD, he accidentally touched his hand to his mouth, nose or possibly eye, ingesting a small amount, and discovered its powerful effects.